The Rise of Bitcoin DeFi: A 2025 Outlook

Yele Bademosi
March 24, 2025
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Bitcoin DeFi Growth

The Next Big Thing in Crypto

If you thought Bitcoin was just digital gold, think again. Bitcoin-native decentralized finance (DeFi) is on the verge of a massive breakout, and 2025 could be the year it truly takes off.

With institutional adoption of Bitcoin (BTC) accelerating and its DeFi ecosystem maturing, industry experts are predicting a seismic shift. From staking to novel DeFi strategies, Bitcoin is no longer just a store of value—it’s transforming into the backbone of decentralized finance.

Bitcoin Staking: A Multi-Billion Dollar Goldmine

Imagine earning a steady yield just for holding Bitcoin. That’s the premise of Bitcoin staking, and it’s becoming a game-changer.

As of December 2024, Bitcoin staking commands around $5.5 billion in total value locked (TVL), according to Staking Rewards. But that’s just the beginning. Experts predict the total market opportunity could reach a staggering $200 billion.

“Everything aligns for Bitcoin staking being a significant market,” says Matt Hougan, Head of Research at Bitwise.

Why the hype? Simple: demand for Bitcoin yield is skyrocketing. Even a modest 3% yield on Bitcoin holdings makes for an attractive investment in a world of dwindling returns elsewhere.

According to Alexei Zamyatin, CEO of Build on Bitcoin, BTC DeFi’s TVL could surge by 300x, potentially redefining how institutions view and utilize their Bitcoin holdings.

Bitcoin DeFi GrowthBitcoin DeFi Growth
Source: DefiLlama

Institutional FOMO: The Catalyst for Growth

Big money is already flooding into Bitcoin, and it’s about to get even bigger.

Why Institutions Are Jumping In

  • Bitcoin ETFs are booming – In 2024, BTC price surged past $100,000, with over $100 billion funneled into spot Bitcoin ETFs.
  • Layer-2 solutions are gaining traction – Networks like Babylon and protocols like EigenLayer (which supports wrapped BTC as collateral) are making Bitcoin staking institutionally viable.
  • Regulatory clarity is improving – As Bitcoin goes mainstream, traditional finance players are looking for new ways to earn yield while staying compliant.

“Bitcoin’s all-time high will spark renewed interest in crypto from institutions and regulators alike. This should reinvigorate the entire crypto sector in 2025.”
Dean Tribble, CEO of Agoric

One example? Asset manager Valour launched a Bitcoin-staking ETF in Europe, offering yields as high as 5.65% APR.

Whether the U.S. follows suit remains to be seen, but one thing’s for sure: Bitcoin staking is no longer just for crypto natives—Wall Street is paying attention.

Bitcoin Staking ETFBitcoin Staking ETF
Source: Valour

Bitcoin DeFi: Ready for Prime Time

Bitcoin’s DeFi space is no longer just an idea—it’s here, and it’s thriving.

The Rise of Liquid Staking Tokens

Liquid staking tokens (LSTs) allow users to stake Bitcoin while keeping their assets liquid for other DeFi activities. Currently, BTC LSTs hold over $2.5 billion in TVL, and that number is expected to rise sharply.

Expanding Bitcoin’s DeFi Universe

More and more Bitcoin Layer-2 solutions are enabling DeFi functionality, including:

  • RSK, Merlin, and Stacks – Hosting decentralized exchanges, lending platforms, and advanced derivatives.
  • Sovryn – An all-in-one Bitcoin-native DeFi platform.
  • Surf – A Bitcoin-based derivatives protocol.

“We’re going to see novel DeFi strategies emerge with Bitcoin as collateral—from simple yield-bearing assets to advanced trading strategies.”
Jacob Phillips, Co-founder of Lombard

Looking Ahead: Could Bitcoin DeFi Redefine Finance?

If Bitcoin staking becomes the benchmark for DeFi lending and borrowing, it would challenge U.S. Treasury bonds as the ‘risk-free rate’.

That’s not just bullish—it’s revolutionary.

With the Bitcoin ecosystem maturing rapidly, 2025 could be the year Bitcoin finally becomes more than just digital gold. It could become the foundation of the next wave of DeFi.

Are you ready?


Related: Bitcoin yield opportunities are booming — Here’s what to watch for

Author Yele Bademosi